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Symptoms and signs include: Decreased libido Erectile dysfunction Infertility Loss of muscle mass Fatigue Mood changes (irritability, depression or anxiety) Also, ADA guidelines added a new section on female dysfunction with recommendations for depression, anxiety, recurring urinary tract infections and screening for symptoms of genitourinary syndrome of menopause

Arthritis Rheumatol (2017) 69(8):152137

But with age, like many other functions, this antioxidant production can slow down and leave cells more susceptible to harmful free radicals

Mozzanica N, Tadini G, Radaelli A, Negri M, Pigatto P, Morelli M,

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exendin-4 treatment, while the latter resulted in increased localization to late endosomes and lysosomes (Fig